Christopher Chidley

An enhanced isothermal amplification assay for viral detection

Jason Qian, Sarah A. Boswell, Christopher Chidley et al. · Nature Communications · 2020 · 168 citations · Full text

Directed evolution of O6-alkylguanine-DNA alkyltransferase for applications in protein labeling

Thomas Gronemeyer, Christopher Chidley, Alexandre Juillerat et al. · Protein Engineering Design and Selection · 2006 · 148 citations · Full text

Protein Expression, Biochemistry, Molecular Biological Method +13

A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity

Adam C. Palmer, Christopher Chidley, Peter K. Sorger · eLife · 2019 · 136 citations · Full text

Drug Additivity, High Fractional Cell, Curative Cancer Therapies +14

A yeast-based screen reveals that sulfasalazine inhibits tetrahydrobiopterin biosynthesis

Christopher Chidley, Hirohito Haruki, Miriam Grønlund Pedersen et al. · Nature Chemical Biology · 2011 · 122 citations · Full text

Yeast-based Screen Reveals, Biosynthesis, Biochemistry +3

Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells

Luca Gerosa, Christopher Chidley, Fabian Fröhlich et al. · Cell Systems · 2020 · 112 citations · Full text