Michal Bitman

Rifampicin Does not Significantly Affect the Expression of Small Heterodimer Partner in Primary Human Hepatocytes

Petr Pávek, Lucie Stejskalová, Lucie Krausová et al. · Frontiers in Pharmacology · 2012 · 378 citations · Full text

Medicine, Molecular Biology, Pharmacology +14

Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug‐metabolizing cytochrome P450 enzymes

Alice Rulcová, Ilona Prokopová, Lucie Krausová et al. · Journal of Thrombosis and Haemostasis · 2010 · 55 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: A possible cause of valproic acid-induced osteomalacia?

Radim Vrzal, Aneta Dořičáková, Aneta Novotná et al. · Toxicology Letters · 2010 · 42 citations

Medicine, Endocrinology, Pharmacokinetics +14

U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells

Tomáš Smutný, Michal Bitman, Michal Urban et al. · Archives of Toxicology · 2014 · 30 citations

Life Sciences, Molecular Biology, Pharmacology +12