Susan K. Clark

Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas

Claire Palles, Jean‐Baptiste Cazier, Kimberley Howarth et al. · Nature Genetics · 2012 · 986 citations · Full text

Guidelines for the clinical management of familial adenomatous polyposis (FAP)

Hans F. A. Vasen, Gabriela Möslein, Ángel Alonso et al. · Gut · 2008 · 691 citations · Full text

Gastrointestinal Oncology, Familial Adenomatous Polyposis, Genetics +7

The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis

Hanan Lamlum, Mohammad Ilyas, Andrew Rowan et al. · Nature Medicine · 1999 · 370 citations

Allelic Variant, Somatic Mutation, Somatic Variant +10

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

Hayley L. Belnoue-Davis, Shazia Irshad, Mukesh Bansal et al. · Nature Medicine · 2014 · 284 citations · Full text

Lineage Plasticity, Medicine, Colorectal Cancer +10

Eicosapentaenoic acid reduces rectal polyp number and size in familial adenomatous polyposis

Nicholas West, Susan K. Clark, R K S Phillips et al. · Gut · 2010 · 238 citations