C. Doucet

Esters and Amides of 6-(Chloromethyl)-2-oxo-2<i>H</i>-1-benzopyran-3-carboxylic Acid as Inhibitors of α-Chymotrypsin:  Significance of the “Aromatic” Nature of the Novel Ester-Type Coumarin for Strong Inhibitory Activity

Lionel Pochet, C. Doucet, M. Schynts et al. · Journal of Medicinal Chemistry · 1996 · 97 citations · Full text

6-Substituted 2-Oxo-2<i>H</i>-1-benzopyran-3-carboxylic Acid as a Core Structure for Specific Inhibitors of Human Leukocyte Elastase

C. Doucet, Lionel Pochet, N. Thierry et al. · Journal of Medicinal Chemistry · 1999 · 61 citations

Coumarinic derivatives as mechanism-based inhibitors of α-chymotrypsin and human leukocyte elastase

Lionel Pochet, C. Doucet, Georges Dive et al. · Bioorganic & Medicinal Chemistry · 2000 · 48 citations · Full text

Inflammation, Medicinal Chemistry, Anti-inflammatory +11

Inhibition of human leukocyte elastase by functionalized N-aryl-3,3-dihalogenoazetidin-2-ones. Stereospecific synthesis and chiral recognition of dissymmetrically C3-substituted β-lactams

C. Doucet, Isabelle Vergely, Michèle Reboud‐Ravaux et al. · Tetrahedron Asymmetry · 1997 · 17 citations

Molecular Pharmacology, Medicinal Chemistry, Bioorganic Chemistry +13

Synthesis and Inhibition of Human Leucocyte Elastase by Functionalized <i>N</i>-Aryl Azetidin-2-ones: Effect of Different Substituents on the Aromatic Ring

Roger Joyeau, Anasse Felk, S Guilaume et al. · Journal of Pharmacy and Pharmacology · 1996 · 11 citations · Full text