Eric P. Griffin

Discovery and Characterization of Novel, Potent, Non-Peptide Parathyroid Hormone-1 Receptor Antagonists

Iain M. McDonald, Carol Austin, Ildiko M. Buck et al. · Journal of Medicinal Chemistry · 2007 · 51 citations · Full text

Pth2 Receptors, Medicinal Chemistry, Biochemistry +13

Optimization of 1,3,4-Benzotriazepine-Based CCK₂ Antagonists to Obtain Potent, Orally Active Inhibitors of Gastrin-Mediated Gastric Acid Secretion

Iain M. McDonald, J.W. Black, Ildiko M. Buck et al. · Journal of Medicinal Chemistry · 2007 · 36 citations · Full text

Human Cck2 Receptors, Gastrointestinal Pharmacology, Gastroenterology +16

Novel, Achiral 1,3,4-Benzotriazepine Analogues of 1,4-Benzodiazepine-Based CCK₂ Antagonists That Display High Selectivity over CCK₁ Receptors

Iain M. McDonald, Carol Austin, Ildiko M. Buck et al. · Journal of Medicinal Chemistry · 2006 · 35 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Achiral 1,3,4-Benzotriazepine +12

Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template

John Spencer, John D. Gaffen, Eric P. Griffin et al. · Bioorganic & Medicinal Chemistry · 2007 · 22 citations · Full text

1,3,5-Benzotriazepine-2,4-dione Template, Functional Selectivity, Medicine +8

Optimization of the in Vitro and in Vivo Properties of a Novel Series of 2,4,5-Trisubstituted Imidazoles as Potent Cholecystokinin-2 (CCK₂) Antagonists

Ildiko M. Buck, J.W. Black, Tracey Cooke et al. · Journal of Medicinal Chemistry · 2005 · 19 citations · Full text

Pharmaceutical Science, Receptor Antagonist, Pharmacotherapy +17