Lan Lai

Activation of miR-34a/SIRT1/p53 signaling contributes to cochlear hair cell apoptosis: implications for age-related hearing loss

Hao Xiong, Jiaqi Pang, Haidi Yang et al. · Neurobiology of Aging · 2015 · 122 citations

Age-related Hearing Loss, Developmental Biology, Health Sciences +12

Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis

Hao Xiong, Suijun Chen, Lan Lai et al. · Neurobiology of Aging · 2019 · 114 citations

Age-related Hearing Loss, Mitophagy, Developmental Biology +13

SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy

Jiaqi Pang, Hao Xiong, Yongkang Ou et al. · Neurobiology of Aging · 2019 · 80 citations

Cell Autophagy, Mitophagy, Autophagy +11

Activation of miR-34a impairs autophagic flux and promotes cochlear cell death via repressing ATG9A: implications for age-related hearing loss

Jiaqi Pang, Hao Xiong, Peiliang Lin et al. · Cell Death and Disease · 2017 · 73 citations · Full text

SIRT1 expression in the cochlea and auditory cortex of a mouse model of age-related hearing loss

Hao Xiong, Min Dai, Yongkang Ou et al. · Experimental Gerontology · 2013 · 59 citations

Auditory Processing, Developmental Biology, Health Sciences +13