Activation of miR-34a/SIRT1/p53 signaling contributes to cochlear hair cell apoptosis: implications for age-related hearing loss

Transactivation of miR-34a by p53 Broadly Influences Gene Expression and Promotes Apoptosis

Tsung-Cheng Chang, Erik A. Wentzel, Oliver A. Kent et al. · Molecular Cell · 2007 · 2K citations · Full text

Life Sciences, Genetics, Molecular Biology +14

p53 mutant mice that display early ageing-associated phenotypes

Stuart D. Tyner, Sundaresan Venkatachalam, Jene Choi et al. · Nature · 2002 · 1.4K citations

Education, Genetics, Molecular Genetics +14

miR-34a repression of SIRT1 regulates apoptosis

Munekazu Yamakuchi, Marcella Ferlito, Charles J. Lowenstein · Proceedings of the National Academy of Sciences · 2008 · 1.3K citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

Sung Jun Park, Faiyaz Ahmad, Andrew Philp et al. · Cell · 2012 · 1.3K citations · Full text

Life Sciences, Biochemistry, Nutritional Sciences +15

MicroRNA-34a regulates cardiac ageing and function

Reinier A. Boon, Kazuma Iekushi, Stefanie Lechner et al. · Nature · 2013 · 817 citations

Education, Cardiology, Molecular Biology +10