Michael W. Hofmann

The protein-conducting channel in the membrane of the endoplasmic reticulum is open laterally toward the lipid bilayer

Bruno Martoglio, Michael W. Hofmann, Josef Brunner et al. · Cell · 1995 · 252 citations · Full text

Natural Sciences, Biochemistry, Biophysics +13

A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models

Vijaykumar M. Baragi, Gabriele Becher, Alison M. Bendele et al. · Arthritis & Rheumatism · 2009 · 173 citations

Medicine, Orthopaedic Surgery, Pharmacology +16

Target-induced formation of neuraminidase inhibitors from <i>in vitro</i> virtual combinatorial libraries

Matthias Hochgürtel, Heiko Kroth, Dorothea Piecha et al. · Proceedings of the National Academy of Sciences · 2002 · 136 citations · Full text

Pharmacy, Medicinal Chemistry, Combinatorial Chemistry +16

Primary structure and functional expression of the α‐, β‐, γ‐, δ‐ and ɛ‐subunits of the acetylcholine receptor from rat muscle

Veit Witzemann, Elke Stein, Brigitte Barg et al. · European Journal of Biochemistry · 1990 · 111 citations

Life Sciences, Biochemistry, Physiology +17

Ketones as Building Blocks for Dynamic Combinatorial Libraries:  Highly Active Neuraminidase Inhibitors Generated via Selection Pressure of the Biological Target

Matthias Hochgürtel, Ralf Biesinger, Heiko Kroth et al. · Journal of Medicinal Chemistry · 2003 · 104 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17