Frances Lu

Structure and Dynamics of NBD1 from CFTR Characterized Using Crystallography and Hydrogen/Deuterium Exchange Mass Spectrometry

H.A. Lewis, Cheng Wang, Xiaoliang Zhao et al. · Journal of Molecular Biology · 2009 · 129 citations

Life Sciences, Biochemistry, Molecular Biology +12

Structures of a minimal human CFTR first nucleotide-binding domain as a monomer, head-to-tail homodimer, and pathogenic mutant

S. Atwell, Christie G. Brouillette, K. Conners et al. · Protein Engineering Design and Selection · 2010 · 99 citations

Life Sciences, Biochemistry, Molecular Biology +14

Structural basis for GPR40 allosteric agonism and incretin stimulation

Joseph D. Ho, Betty Chau, Logan Rodgers et al. · Nature Communications · 2018 · 85 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Computationally Designed Bispecific Antibodies using Negative State Repertoires

Andrew Leaver‐Fay, Karen Froning, S. Atwell et al. · Structure · 2016 · 63 citations · Full text

Pharmacy, Biotechnology, Immunology +14

Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1<i>S</i>,2<i>S</i>,5<i>R</i>,6<i>S</i>-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures

James A. Monn, Lourdes Prieto, Lorena Taboada et al. · Journal of Medicinal Chemistry · 2015 · 61 citations

Medicine, Medicinal Chemistry, Pharmacology +16