Janine J. Leffert

Uridine phosphorylase (-/-) murine embryonic stem cells clarify the key role of this enzyme in the regulation of the pyrimidine salvage pathway and in the activation of fluoropyrimidines.

Deliang Cao, Rosalind L. Russell, Dekai Zhang et al. · PubMed · 2002 · 69 citations

Medicine, Oncology, Pharmacology +13

Abnormalities in Uridine Homeostatic Regulation and Pyrimidine Nucleotide Metabolism as a Consequence of the Deletion of the Uridine Phosphorylase Gene

Deliang Cao, Janine J. Leffert, James L. McCabe et al. · Journal of Biological Chemistry · 2005 · 65 citations · Full text

Life Sciences, Biochemistry, Molecular Genetics +11

Increased peripheral blood expression of electron transport chain genes in bipolar depression

Robert D. Beech, Lori Lowthert, Janine J. Leffert et al. · Bipolar Disorders · 2010 · 61 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation

Lori Lowthert, Janine J. Leffert, Aiping Lin et al. · Biology of Mood & Anxiety Disorders · 2012 · 56 citations · Full text

Medicine, Pharmacology, Psychiatry +15

Gene-expression differences in peripheral blood between lithium responders and non-responders in the Lithium Treatment-Moderate dose Use Study (LiTMUS)

Robert D. Beech, Janine J. Leffert, Louisa G. Sylvia et al. · The Pharmacogenomics Journal · 2013 · 50 citations

Medicine, Genetics, Pharmacology +12