Glucocerebrosidase gene-deficient mouse recapitulates Gaucher disease displaying cellular and molecular dysregulation beyond the macrophage

Pramod K. Mistry, Jun Liu, Mei Yang, +20

Proceedings of the National Academy of Sciences

SclerostinImmunologySevere OsteoporosisPathologyCell Death +18

Pathway analysis using random forests classification and regression

Herbert Pang, Aiping Lin, Matthew Holford, +5

Bioinformatics

Impaired Interferon Signaling in Dendritic Cells From Older Donors Infected In Vitro With West Nile Virus

Feng Qian, Xiaomei Wang, Lin Zhang, +4

The Journal of Infectious Diseases

MedicineYounger DonorsPathogenesisViral PathogenesisImmunology +10

Pumilio 1 Suppresses Multiple Activators of p53 to Safeguard Spermatogenesis

Dong Chen, Wei Zheng, Aiping Lin, +3

Current Biology

SpermatogenesisDevelopmental BiologyGeneticsGameteMolecular Genetics +8

Rapid generation of maturationally synchronized human dendritic cells: contribution to the clinical efficacy of extracorporeal photochemotherapy

Carole L. Berger, Kristin Elizabeth Hoffmann, Juan Gabriel Vasquez, +13

Blood

Decreased Transcription of ChREBP-α/β Isoforms in Abdominal Subcutaneous Adipose Tissue of Obese Adolescents With Prediabetes or Early Type 2 Diabetes

Romy Kursawe, Sonia Caprio, Cosimo Giannini, +7

Diabetes

NutritionMetabolic DisorderEarly Type 2Glucose ToleranceInsulin Signaling +19

Regulation of Mitochondrial Biogenesis by Lipoprotein Lipase in Muscle of Insulin-Resistant Offspring of Parents With Type 2 Diabetes

Katsutaro Morino, Kitt Falk Petersen, Saki Sono, +11

Diabetes

Lipoprotein LipaseGeneticsInsulin SignalingOxidative StressMetabolic Syndrome +18

Increased peripheral blood expression of electron transport chain genes in bipolar depression

Robert D. Beech, Lori Lowthert, Janine J. Leffert, +15

Bipolar Disorders

The Kinases MEKK2 and MEKK3 Regulate Transforming Growth Factor-β-Mediated Helper T Cell Differentiation

Xing Chang, Fang Liu, Xiaofang Wang, +3

Immunity

Signal TransductionCell RegulationLymphocyte DevelopmentImmune Cell DevelopmentReceptor Tyrosine Kinase +9

Increased ratio of anti-apoptotic to pro-apoptotic Bcl2 gene-family members in lithium-responders one month after treatment initiation

Lori Lowthert, Janine J. Leffert, Aiping Lin, +9

Biology of Mood & Anxiety Disorders