Negar Sheikh‐Zeineddini

Small molecule inhibitor of c-Myc 10058-F4 inhibits proliferation and induces apoptosis in acute leukemia cells, irrespective of PTEN status

Davood Bashash, Mohammad Sayyadi, Ava Safaroghli‐Azar et al. · The International Journal of Biochemistry & Cell Biology · 2019 · 46 citations

Hematological Malignancy, Acute Leukemia Cells, Apoptosis +10

Suppression of c‐Myc using 10058‐F4 exerts caspase‐3‐dependent apoptosis and intensifies the antileukemic effect of vincristine in pre‐B acute lymphoblastic leukemia cells

Negar Sheikh‐Zeineddini, Davood Bashash, Ava Safaroghli‐Azar et al. · Journal of Cellular Biochemistry · 2019 · 37 citations

Hematological Malignancy, C-myc-mediated Suppression, Exerts Caspase‐3‐dependent Apoptosis +15

C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4

Negar Sheikh‐Zeineddini, Ava Safaroghli‐Azar, Sina Salari et al. · European Journal of Pharmacology · 2019 · 26 citations

Cell Autophagy, Anti-tumor Effect, Medicine +11

Synergistic Effects of PI3K and c-Myc Co-targeting in Acute Leukemia: Shedding New Light on Resistance to Selective PI3K-δ Inhibitor CAL-101

Niknam Riyahi, Ava Safaroghli‐Azar, Negar Sheikh‐Zeineddini et al. · Cancer Investigation · 2019 · 15 citations

P53 Status, Immunology, Cell Death +19