C-Myc inhibition sensitizes pre-B ALL cells to the anti-tumor effect of vincristine by altering apoptosis and autophagy: Proposing a probable mechanism of action for 10058-F4

Myc suppression of the p21Cip1 Cdk inhibitor influences the outcome of the p53 response to DNA damage

Joan Seoane, H. Carl Le, Joan Massagué · Nature · 2002 · 683 citations

Life Sciences, Genetics, Molecular Biology +17

Gene-Expression Patterns in Drug-Resistant Acute Lymphoblastic Leukemia Cells and Response to Treatment

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Medicine, Oncology, Pharmacology +14

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

Zirong Li, Sara Van Calcar, Chunxu Qu et al. · Proceedings of the National Academy of Sciences · 2003 · 522 citations · Full text

Life Sciences, Cancer Biology, Oncology +17

Antisense strategy shows that Mcl-1 rather than Bcl-2 or Bcl-xL is an essential survival protein of human myeloma cells

Sophie Derenne, Brett P. Monia, Nicholas M. Dean et al. · Blood · 2002 · 430 citations · Full text

Medicine, Cancer Biology, Cell Biology +10

CDK2-Dependent Phosphorylation of FOXO1 as an Apoptotic Response to DNA Damage

Haojie Huang, Kevin M. Regan, Zhenkun Lou et al. · Science · 2006 · 338 citations

Life Sciences, Cell Biology, Molecular Biology +17