Elirosa Minniti

Pharmacophore Hybridization To Discover Novel Topoisomerase II Poisons with Promising Antiproliferative Activity

José Antonio Ortega, Laura Riccardi, Elirosa Minniti et al. · Journal of Medicinal Chemistry · 2017 · 36 citations · Full text

Medicinal Chemistry, Hybrid Topoii Poisons, Pharmacophore Hybridization +11

An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512

Giulia Palermo, Elirosa Minniti, Maria Laura Greco et al. · Chemical Communications · 2015 · 35 citations · Full text

Drug Target, Molecular Biology, Pharmacotherapy +18

Novel, Potent, and Druglike Tetrahydroquinazoline Inhibitor That Is Highly Selective for Human Topoisomerase II α over β

José Antonio Ortega, José M. Arencibia, Elirosa Minniti et al. · Journal of Medicinal Chemistry · 2020 · 26 citations · Full text

Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα

Elirosa Minniti, Jo Ann W. Byl, Laura Riccardi et al. · Bioorganic & Medicinal Chemistry Letters · 2017 · 23 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Biochemistry +7

Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ

Alexandria A. Oviatt, A. K. Jissy, Elirosa Minniti et al. · Bioorganic & Medicinal Chemistry Letters · 2018 · 16 citations · Full text

Molecular Pharmacology, Biochemistry, Topoisomerase Iiα +6