Andrea C. Mislak

Crystal Structures of HIV-1 Reverse Transcriptase with Picomolar Inhibitors Reveal Key Interactions for Drug Design

Kathleen M. Frey, Mariela Bollini, Andrea C. Mislak et al. · Journal of the American Chemical Society · 2012 · 52 citations · Full text

Bioorganic Chemistry, Molecular Biology, Antiviral Drug +20

Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase γ

Christal D. Sohl, Michał R. Szymański, Andrea C. Mislak et al. · Proceedings of the National Academy of Sciences · 2015 · 45 citations · Full text

Dna, Viral Polymerase Structure, Dna Analysis +19

Potent Inhibitors Active against HIV Reverse Transcriptase with K101P, a Mutation Conferring Rilpivirine Resistance

William T. Gray, Kathleen M. Frey, Sarah B. Laskey et al. · ACS Medicinal Chemistry Letters · 2015 · 26 citations · Full text

Immunology, Molecular Biology, New Crystal Structure +18

Insights into the Molecular Mechanism of Polymerization and Nucleoside Reverse Transcriptase Inhibitor Incorporation by Human PrimPol

Andrea C. Mislak, Karen S. Anderson · Antimicrobial Agents and Chemotherapy · 2015 · 24 citations · Full text

Molecular Biology, Mtdna Pol γ, Nucleic Acid Chemistry +16

Probing the molecular mechanism of action of the HIV-1 reverse transcriptase inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) using pre-steady-state kinetics

Yagmur Muftuoglu, Christal D. Sohl, Andrea C. Mislak et al. · Antiviral Research · 2014 · 21 citations · Full text

Pre-steady-state Kinetics, Biochemistry, Natural Sciences +7