Bridgette Craig

Efficient Synthesis of NK₁ Receptor Antagonist Aprepitant Using a Crystallization-Induced Diastereoselective Transformation

Karel M. J. Brands, Joseph F. Payack, Jonathan D. Rosen et al. · Journal of the American Chemical Society · 2003 · 156 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Enantiospecific and regioselective opening of 2-alkyl nosylaziridines by indoles mediated by boron trifluoride. Application to a practical synthesis of a GnRH antagonist

Roger N. Farr, Ramon J. Alabaster, John Y. L. Chung et al. · Tetrahedron Asymmetry · 2003 · 48 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14

Isotopic Perturbation of Intramolecular Hydrogen Bonds in Rigid 1,3-Diols:  NMR Studies Reveal Unusually Large Equilibrium Isotope Effects

Bridgette Craig, Matthew U. Janssen, Brian M. Wickersham et al. · The Journal of Organic Chemistry · 1996 · 43 citations

Natural Sciences, Biochemistry, Chemistry +11

Synthesis of a Potent hNK-1 Receptor Antagonist via an S_N2 Reaction of an Enantiomerically Pure α-Alkoxy Sulfonate

Todd D. Nelson, Jonathan D. Rosen, Jacqueline H. Smitrovich et al. · Organic Letters · 2004 · 21 citations

Pharmacy, Chemistry, Medicinal Chemistry +10

Syntheses of morpholine-2,3-diones and 2-hydroxymorpholin-3-ones: intermediates in the synthesis of aprepitant

Todd D. Nelson, Jonathan D. Rosen, Karel M. J. Brands et al. · Tetrahedron Letters · 2004 · 18 citations

Natural Sciences, Chemistry, Medicinal Chemistry +3