Christopher J. O’Conor

TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading

Christopher J. O’Conor, Holly A. Leddy, Halei C. Benefield et al. · Proceedings of the National Academy of Sciences · 2014 · 468 citations · Full text

Engineering, Articular Chondrocytes, Trpv4-mediated Ca +19

Recurrent WNT pathway alterations are frequent in relapsed small cell lung cancer

Alex H. Wagner, Siddhartha Devarakonda, Zachary L. Skidmore et al. · Nature Communications · 2018 · 165 citations · Full text

Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis

Christopher J. O’Conor, Sendhilnathan Ramalingam, Nicole A. Zelenski et al. · Scientific Reports · 2016 · 140 citations · Full text

Increased susceptibility of Trpv4-deficient mice to obesity and obesity-induced osteoarthritis with very high-fat diet

Christopher J. O’Conor, Timothy M. Griffin, Wolfgang Liedtke et al. · Annals of the Rheumatic Diseases · 2012 · 100 citations

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Robert J. Nims, Lara Pferdehirt, Noelani Ho et al. · Science Advances · 2021 · 78 citations · Full text

Tissue Engineering, Autonomous Drug Delivery, Engineering +22