Robert J. Nims

Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis

Whasil Lee, Robert J. Nims, Alireza Savadipour et al. · Proceedings of the National Academy of Sciences · 2021 · 252 citations · Full text

Life Sciences, Orthopaedic Surgery, Orthopedic Surgery +17

Shearing of synovial fluid activates latent TGF-β

Michael B. Albro, A. Cigáň, Robert J. Nims et al. · Osteoarthritis and Cartilage · 2012 · 124 citations · Full text

Life Sciences, Biophysics, Cell Biology +14

Accumulation of Exogenous Activated TGF-β in the Superficial Zone of Articular Cartilage

Michael B. Albro, Robert J. Nims, A. Cigáň et al. · Biophysical Journal · 2013 · 98 citations · Full text

Medicine, Orthopaedic Surgery, Orthopedic Surgery +16

A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues

Robert J. Nims, Lara Pferdehirt, Noelani Ho et al. · Science Advances · 2021 · 88 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +17

Membrane stretch as the mechanism of activation of PIEZO1 ion channels in chondrocytes

Alireza Savadipour, Robert J. Nims, Neda Rashidi et al. · Proceedings of the National Academy of Sciences · 2023 · 77 citations · Full text

Natural Sciences, Biophysics, Cell Biology +17