Niamh L. O’Brien

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Vassily Trubetskoy, Antonio F. Pardiñas, Ting Qi et al. · Nature · 2022 · 2.6K citations · Full text

Psychiatry, Genetics, Psychiatric Genetics +7

Rare coding variants in ten genes confer substantial risk for schizophrenia

Tarjinder Singh, Timothy Poterba, David Curtis et al. · Nature · 2022 · 823 citations · Full text

Allelic Variant, Psychiatry, Risk Prediction +11

Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene dose-sensitive AD suppressor in human brain

Ivan Alić, Pollyanna Goh, Aoife Murray et al. · Molecular Psychiatry · 2020 · 118 citations · Full text

A Rare Functional Noncoding Variant at the GWAS-Implicated MIR137/MIR2682 Locus Might Confer Risk to Schizophrenia and Bipolar Disorder

Jubao Duan, Jianxin Shi, Alessia Fiorentino et al. · The American Journal of Human Genetics · 2014 · 109 citations · Full text

Psychiatry, Genetics, Psychiatric Genetics +9

CACNA1C hypermethylation is associated with bipolar disorder

Anna Starnawska, Ditte Demontis, Anja E. Pen et al. · Translational Psychiatry · 2016 · 57 citations · Full text