Patricia Baxter

Selumetinib in paediatric patients with BRAF-aberrant or neurofibromatosis type 1-associated recurrent, refractory, or progressive low-grade glioma: a multicentre, phase 2 trial

Jason Fangusaro, Arzu Onar‐Thomas, Tina Young Poussaint et al. · The Lancet Oncology · 2019 · 502 citations · Full text

Medicine, Oncology, Pediatrics +16

Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design

Jo Lynne Rokita, Komal S. Rathi, Maria Cardenas et al. · Cell Reports · 2019 · 173 citations · Full text

Medicine, Oncology, Pediatrics +17

A phase II trial of selumetinib in children with recurrent optic pathway and hypothalamic low-grade glioma without NF1: a Pediatric Brain Tumor Consortium study

Jason Fangusaro, Arzu Onar‐Thomas, Tina Young Poussaint et al. · Neuro-Oncology · 2021 · 159 citations · Full text

Medicine, Oncology, Pediatrics +15

Global gene expression profiling confirms the molecular fidelity of primary tumor-based orthotopic xenograft mouse models of medulloblastoma

Xiumei Zhao, Zhigang Liu, Litian Yu et al. · Neuro-Oncology · 2012 · 153 citations · Full text

Life Sciences, Genetics, Oncology +16

Direct Orthotopic Transplantation of Fresh Surgical Specimen Preserves CD133+ Tumor Cells in Clinically Relevant Mouse Models of Medulloblastoma and Glioma

Qin Shu, Kwong‐Kwok Wong, Jack Su et al. · Stem Cells · 2008 · 149 citations · Full text

Medicine, Neuroscience, Oncology +14