Anne S. Kienhuis

Exploring the zebrafish embryo as an alternative model for the evaluation of liver toxicity by histopathology and expression profiling

Marja Driessen, Anne S. Kienhuis, Jeroen L. A. Pennings et al. · Archives of Toxicology · 2013 · 87 citations

Developmental Biology, Hepatology, Medicine +14

Development of a Roadmap for Action on New Approach Methodologies in Risk Assessment

Sylvia E. Escher, Falko Partosch, Sebastian Konzok et al. · EFSA Supporting Publications · 2022 · 85 citations · Full text

Risk Model Validation, Additional Aops/aop Networks, Human Susceptibility +27

Assessing the Metabolic Competence of Sandwich-Cultured Mouse Primary Hepatocytes

Karen Mathijs, Anne S. Kienhuis, Karen Brauers et al. · Drug Metabolism and Disposition · 2009 · 69 citations

A transcriptomics-based hepatotoxicity comparison between the zebrafish embryo and established human and rodent in vitro and in vivo models using cyclosporine A, amiodarone and acetaminophen

Marja Driessen, Alexa P. Vitins, Jeroen L. A. Pennings et al. · Toxicology Letters · 2014 · 68 citations

Developmental Biology, Medicine, Transcriptomics-based Hepatotoxicity Comparison +11

Parallelogram Approach Using Rat-Human In Vitro and Rat In Vivo Toxicogenomics Predicts Acetaminophen-induced Hepatotoxicity in Humans

Anne S. Kienhuis, Marcel C.G. van de Poll, Heleen M. Wortelboer et al. · Toxicological Sciences · 2008 · 55 citations · Full text

Toxicological Mechanism, Oxidative Stress, Toxicology +20