David Barros-Aguirre

Prioritizing multiple therapeutic targets in parallel using automated DNA-encoded library screening

Carl A. Machutta, Christopher S. Kollmann, Kenneth Lind et al. · Nature Communications · 2017 · 74 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

First-Time-in-Human Study and Prediction of Early Bactericidal Activity for GSK3036656, a Potent Leucyl-tRNA Synthetase Inhibitor for Tuberculosis Treatment

David M. Tenero, Geo Derimanov, Alex Carlton et al. · Antimicrobial Agents and Chemotherapy · 2019 · 73 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

Whole Cell Target Engagement Identifies Novel Inhibitors of <i>Mycobacterium tuberculosis</i> Decaprenylphosphoryl-β-<scp>d</scp>-ribose Oxidase

Sarah M. Batt, Mónica Cacho Izquierdo, Julia Castro Pichel et al. · ACS Infectious Diseases · 2015 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

The Tuberculosis Drug Accelerator at year 10: what have we learned?

Bree B. Aldridge, David Barros-Aguirre, Clifton E. Barry et al. · Nature Medicine · 2021 · 62 citations · Full text

Public Health, Pharmacology, Pharmacotherapy +11

Novel Pyrazole-Containing Compounds Active against <i>Mycobacterium tuberculosis</i>

Giovanna Poce, Sara Consalvi, G Venditti et al. · ACS Medicinal Chemistry Letters · 2019 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14