Stefania Faedo

Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo

Christian Heidbreder, Massimiliano Bianchi, Laurent Lacroix et al. · Synapse · 2003 · 74 citations

Medicine, Neuroscience, Pharmacology +17

Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders

Romano Di Fabio, Annalisa Pellacani, Stefania Faedo et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 53 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4′-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain

David R. Thomas, Ellen M. Soffin, Claire Roberts et al. · Neuropharmacology · 2006 · 51 citations

Medicine, Neuroscience, Pharmacology +15

6-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: Dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors

Steven M. Bromidge, Barbara Bertani, Manuela Borriello et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 30 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12

2,4-Dicarboxy-pyrroles as selective non-Competitive mGluR1 antagonists: further characterization of 3,5-Dimethyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-Trimethyl-propyl) ester and structure–Activity relationships

Fabrizio Micheli, Romano Di Fabio, Fabio Bordi et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 24 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +8