Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen‐Chun Liu, +12

Cell

Imbalanced Host ResponseCovid-19 PandemicVirologyCovid-19 EpidemiologyPublic Health +4

A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics

Longlong Si, Haiqing Bai, Melissa Rodas, +35

Nature Biomedical Engineering

Viral DiagnosticsRapid IdentificationMedicineCandidate Antiviral TherapeuticsAntiviral Response +5

SARS-CoV-2 infection in hamsters and humans results in lasting and unique systemic perturbations after recovery

Justin J. Frere, Randal A. Serafini, Kerri D. Pryce, +19

Science Translational Medicine

Unique Systemic PerturbationsHumans ResultsGolden HamsterAllergyLong Covid +12

SARS-CoV-2 launches a unique transcriptional signature from in vitro, ex vivo, and in vivo systems

Daniel Blanco-Melo, Benjamin E. Nilsson-Payant, Wen‐Chun Liu, +5

Viral EvolutionA VirusEmerging Infectious DiseasesVivo SystemsViral Pathogenesis +13

Leveraging the antiviral type I interferon system as a first line of defense against SARS-CoV-2 pathogenicity

Daisy A. Hoagland, Rasmus Møller, Skyler Uhl, +10

Immunity

MedicineFirst LineImmunologyViral PathogenesisAntiviral Therapy +9

SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium

Anne Z. Eriksen, Rasmus Møller, Bar Makovoz, +3

Cell stem cell

Viral PathogenesisPathologyVirologyViral Structural ProteinMedicine +2

Human organ chip-enabled pipeline to rapidly repurpose therapeutics during viral pandemics

Longlong Si, Haiqing Bai, Melissa Rodas, +29

EngineeringInflammatory Lung DiseaseViral DiagnosticsSynthetic VirologyViral Pathogenesis +20

Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2

Liuliu Yang, Benjamin E. Nilsson-Payant, Yuling Han, +23

Stem Cell Reports

Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection

Kristina Dobrindt, Daisy A. Hoagland, Carina Seah, +21

Stem Cell Reports

Immune memory from SARS-CoV-2 infection in hamsters provides variant-independent protection but still allows virus transmission

Shu Horiuchi, Kohei Oishi, Lucía Carrau, +4

Science Immunology