Alejandra Herrera-Morandé

Reconstructed ancestral enzymes reveal that negative selection drove the evolution of substrate specificity in ADP-dependent kinases

Víctor Castro‐Fernández, Alejandra Herrera-Morandé, Ricardo A. Zamora et al. · Journal of Biological Chemistry · 2017 · 31 citations · Full text

Life Sciences, Evolutionary Biology, Microbiology +17

Crystal Structure, SAXS and Kinetic Mechanism of Hyperthermophilic ADP-Dependent Glucokinase from Thermococcus litoralis Reveal a Conserved Mechanism for Catalysis

Jaime Andrés Rivas‐Pardo, Alejandra Herrera-Morandé, Víctor Castro‐Fernández et al. · PLoS ONE · 2013 · 26 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Structure and inhibition of SARS-CoV-1 and SARS-CoV-2 main proteases by oral antiviral compound AG7404

Montserrat Fàbrega-Ferrer, Alejandra Herrera-Morandé, Sara Muriel-Goñi et al. · Antiviral Research · 2022 · 24 citations · Full text

Life Sciences, Infectious Diseases, Medicinal Chemistry +13

Bifunctional<scp>ADP</scp>‐dependent phosphofructokinase/glucokinase activity in the order<i><scp>M</scp>ethanococcales</i>– biochemical characterization of the mesophilic enzyme from<i><scp>M</scp>ethanococcus maripaludis</i>

Víctor Castro‐Fernández, Felipe Bravo‐Moraga, Alejandra Herrera-Morandé et al. · FEBS Journal · 2014 · 21 citations · Full text

Life Sciences, Biochemistry, Microbiology +11

Tuning of Conformational Dynamics Through Evolution-Based Design Modulates the Catalytic Adaptability of an Extremophilic Kinase

Ricardo A. Zamora, César A. Ramírez‐Sarmiento, Víctor Castro‐Fernández et al. · ACS Catalysis · 2020 · 12 citations

Life Sciences, Biochemistry, Evolutionary Biology +17