Zachary Maben

Editing the immunopeptidome of melanoma cells using a potent inhibitor of endoplasmic reticulum aminopeptidase 1 (ERAP1)

Despoina Koumantou, Eilon Barnea, Adrian Martín‐Esteban et al. · Cancer Immunology Immunotherapy · 2019 · 55 citations · Full text

Protein Function, Signal Transduction, Potent Inhibitor +6

Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1

Zachary Maben, Richa Arya, Digamber Rane et al. · Journal of Medicinal Chemistry · 2019 · 50 citations · Full text

Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism

Zachary Maben, Richa Arya, Dimitris Georgiadis et al. · Nature Communications · 2021 · 41 citations · Full text

Adrenocorticotropic Hormone (ACTH) Responses Require Actions of the Melanocortin-2 Receptor Accessory Protein on the Extracellular Surface of the Plasma Membrane

Sundeep Malik, Terrance M. Dolan, Zachary Maben et al. · Journal of Biological Chemistry · 2015 · 40 citations · Full text

Critical Role of Interdomain Interactions in the Conformational Change and Catalytic Mechanism of Endoplasmic Reticulum Aminopeptidase 1

Athanasios Stamogiannos, Zachary Maben, Athanasios Papakyriakou et al. · Biochemistry · 2017 · 38 citations

Protein Assembly, Molecular Biology, Open Conformational State +18