R. Brock Fletcher

An anionic, endosome-escaping polymer to potentiate intracellular delivery of cationic peptides, biomacromolecules, and nanoparticles

Brian C. Evans, R. Brock Fletcher, Kameron V. Kilchrist et al. · Nature Communications · 2019 · 87 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17

Structural Optimization of Polymeric Carriers to Enhance the Immunostimulatory Activity of Molecularly Defined RIG-I Agonists

Max E. Jacobson, Kyle W. Becker, Christian R. Palmer et al. · ACS Central Science · 2020 · 37 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Tuning Composition of Polymer and Porous Silicon Composite Nanoparticles for Early Endosome Escape of Anti-microRNA Peptide Nucleic Acids

Isom B. Kelly, R. Brock Fletcher, James R. McBride et al. · ACS Applied Materials & Interfaces · 2020 · 30 citations · Full text

Pharmacy, Materials Science, Pharmaceutics +17

Nonviral <i>In Vivo</i> Delivery of CRISPR-Cas9 Using Protein-Agnostic, High-Loading Porous Silicon and Polymer Nanoparticles

R. Brock Fletcher, Larry D. Stokes, Isom B. Kelly et al. · ACS Nano · 2023 · 30 citations · Full text

Pharmacy, Bioengineering, Biotechnology +17

Preparation, characterization and preliminary pharmacokinetic study of pH-sensitive Hydroxyapatite/Zein nano-drug delivery system for doxorubicin hydrochloride

Liqiong Zha, Beilei Wang, Jiajia Qian et al. · Journal of Pharmacy and Pharmacology · 2020 · 27 citations

Pharmacy, Pharmacokinetics, Pharmacology +17