Luigi Capoferri

A Catalytic Mechanism for Cysteine N-Terminal Nucleophile Hydrolases, as Revealed by Free Energy Simulations

Alessio Lodola, Davide Branduardi, Marco De Vivo et al. · PLoS ONE · 2012 · 78 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Quantum Mechanics/Molecular Mechanics Modeling of Covalent Addition between EGFR–Cysteine 797 and<i>N</i>-(4-Anilinoquinazolin-6-yl) Acrylamide

Luigi Capoferri, Alessio Lodola, Silvia Rivara et al. · Journal of Chemical Information and Modeling · 2015 · 56 citations

Natural Sciences, Chemistry, Pharmacology +17

Application of engineered cytochrome P450 mutants as biocatalysts for the synthesis of benzylic and aromatic metabolites of fenamic acid NSAIDs

Harini Venkataraman, Marlies C. A. Verkade‐Vreeker, Luigi Capoferri et al. · Bioorganic & Medicinal Chemistry · 2014 · 40 citations

Medicine, Biotechnology, Pharmacology +16

Quantum Mechanics/Molecular Mechanics Modeling of Fatty Acid Amide Hydrolase Reactivation Distinguishes Substrate from Irreversible Covalent Inhibitors

Alessio Lodola, Luigi Capoferri, Silvia Rivara et al. · Journal of Medicinal Chemistry · 2013 · 36 citations · Full text

Life Sciences, Biochemistry, Chemistry +17

Insights into regioselective metabolism of mefenamic acid by cytochrome <scp>P</scp>450 <scp>BM</scp>3 mutants through crystallography, docking, molecular dynamics, and free energy calculations

Luigi Capoferri, Rasmus Leth, Ernst ter Haar et al. · Proteins Structure Function and Bioinformatics · 2016 · 32 citations

Medicine, Biochemistry, Pharmacology +17