David Wolloscheck

Synergy between Active Efflux and Outer Membrane Diffusion Defines Rules of Antibiotic Permeation into Gram-Negative Bacteria

Ganesh Krishnamoorthy, Inga V. Leus, Jon W. Weeks et al. · mBio · 2017 · 197 citations · Full text

Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane

Ganesh Krishnamoorthy, David Wolloscheck, Jon W. Weeks et al. · Antimicrobial Agents and Chemotherapy · 2016 · 133 citations · Full text

Membrane Biophysics, Antimicrobial Susceptibility, Antibiotics +14

Reviving Antibiotics: Efflux Pump Inhibitors That Interact with AcrA, a Membrane Fusion Protein of the AcrAB-TolC Multidrug Efflux Pump

Narges Abdali, Jerry M. Parks, Keith M. Haynes et al. · ACS Infectious Diseases · 2016 · 123 citations · Full text

Protein Secretion, Antimicrobial Drug Discovery, Membrane Fusion Protein +15

Bifurcation kinetics of drug uptake by Gram-negative bacteria

David A. Westfall, Ganesh Krishnamoorthy, David Wolloscheck et al. · PLoS ONE · 2017 · 79 citations · Full text

Bifurcation Kinetics, Biophysical Modeling, Biochemistry +15

Kinetic Control of Quorum Sensing in <i>Pseudomonas aeruginosa</i> by Multidrug Efflux Pumps

David Wolloscheck, Ganesh Krishnamoorthy, Jennifer Nguyen et al. · ACS Infectious Diseases · 2017 · 78 citations · Full text

Quorum Sensing Signals, Bacteriology, Antimicrobial Chemotherapy +18