Cynthia D. Sobotka‐Briner

Linear Non-competitive Inhibition of Solubilized Human γ-Secretase by Pepstatin A Methylester, L685458, Sulfonamides, and Benzodiazepines

Gaochao Tian, Cynthia D. Sobotka‐Briner, John R. Zysk et al. · Journal of Biological Chemistry · 2002 · 146 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Mechanism of γ-Secretase Cleavage Activation:  Is γ-Secretase Regulated through Autoinhibition Involving the Presenilin-1 Exon 9 Loop?

Katharine S. Knappenberger, Gaochao Tian, Xiaomei Ye et al. · Biochemistry · 2004 · 53 citations

Life Sciences, Biochemistry, Molecular Biology +16

De Novo Design of a Picomolar Nonbasic 5-HT_1BReceptor Antagonist

David A. Nugiel, Jennifer R. Krumrine, Daniel C. Hill et al. · Journal of Medicinal Chemistry · 2010 · 23 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist

Minli Zhang, Diansong Zhou, Yi Wang et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 19 citations

Medicine, Medicinal Chemistry, Pharmacology +10

COOH-terminal methylation of lamin B and inhibition of methylation by farnesylated peptides corresponding to lamin B and other CAAX motif proteins.

Cynthia D. Sobotka‐Briner, Daniel Chelsky · Journal of Biological Chemistry · 1992 · 18 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16