Role for Interferon-γ in the Immunomodulatory Activity of Human Bone Marrow Mesenchymal Stem Cells

Mauro Krampera, Lorenzo Cosmi, Roberta Angeli, +11

Stem Cells

T-regulatory CellImmune RegulationImmunologyImmunologic MechanismInnate Immunity +19

Human interleukin 17–producing cells originate from a CD161+CD4+ T cell precursor

Lorenzo Cosmi, Raffaele De Palma, Veronica Santarlasci, +17

The Journal of Experimental Medicine

InflammationAutoimmune DiseaseIl-1 BetaLymphocyte DevelopmentImmune Cell Development +13

Toll-Like Receptors 3 and 4 Are Expressed by Human Bone Marrow-Derived Mesenchymal Stem Cells and Can Inhibit Their T-Cell Modulatory Activity by Impairing Notch Signaling

Francesco Liotta, Roberta Angeli, Lorenzo Cosmi, +16

Stem Cells

Human CD8+CD25+ thymocytes share phenotypic and functional features with CD4+CD25+ regulatory thymocytes

Lorenzo Cosmi, Francesco Liotta, Elena Lazzeri, +10

Blood

Identification of a novel subset of human circulating memory CD4+ T cells that produce both IL-17A and IL-4

Lorenzo Cosmi, Laura Maggi, Veronica Santarlasci, +12

Journal of Allergy and Clinical Immunology

InflammationImmunological MemoryAutoimmune DiseaseT-regulatory CellImmunology +6

Characterization of human adult stem‐cell populations isolated from visceral and subcutaneous adipose tissue

Silvana Baglioni, Michela Francalanci, Roberta Squecco, +13

The FASEB Journal

Sublingual immunotherapy with <i>Dermatophagoides</i> monomeric allergoid down‐regulates allergen‐specific immunoglobulin E and increases both interferon‐γ‐ and interleukin‐10‐production

Lorenzo Cosmi, Veronica Santarlasci, Roberta Angeli, +9

Clinical & Experimental Allergy

Th2 cells are less susceptible than Th1 cells to the suppressive activity of CD25+ regulatory thymocytes because of their responsiveness to different cytokines

Lorenzo Cosmi, Francesco Liotta, Roberta Angeli, +9

Blood

Functional deficit of T regulatory cells in Fulani, an ethnic group with low susceptibility to <i>Plasmodium falciparum</i> malaria

Maria Gabriella Torcia, Veronica Santarlasci, Lorenzo Cosmi, +20

Proceedings of the National Academy of Sciences

GeneticsMalariaImmune RegulationImmunologyPathology +17

Frequency of regulatory T cells in peripheral blood and in tumour‐infiltrating lymphocytes correlates with poor prognosis in renal cell carcinoma

Francesco Liotta, Mauro Gacci, Francesca Frosali, +14

British Journal of Urology