Fijs W. B. van Leeuwen

Potent activity of carfilzomib, a novel, irreversible inhibitor of the ubiquitin-proteasome pathway, against preclinical models of multiple myeloma

Deborah J. Kuhn, Qing Chen, Peter M. Voorhees et al. · Blood · 2007 · 768 citations · Full text

Medicine, Oncology, Pharmacology +13

Intraoperative Laparoscopic Fluorescence Guidance to the Sentinel Lymph Node in Prostate Cancer Patients: Clinical Proof of Concept of an Integrated Functional Imaging Approach Using a Multimodal Tracer

Henk G. van der Poel, Tessa Buckle, Oscar R. Brouwer et al. · European Urology · 2011 · 330 citations

Medicine, Surgery, Urology +17

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer

Sven Rottenberg, Anders O.H. Nygren, Marina Pajic et al. · Proceedings of the National Academy of Sciences · 2007 · 304 citations · Full text

Medicine, Cancer Biology, Oncology +16

Detection of colorectal polyps in humans using an intravenously administered fluorescent peptide targeted against c-Met

Jacobus Burggraaf, Ingrid M. C. Kamerling, Paul B. Gordon et al. · Nature Medicine · 2015 · 295 citations · Full text

Medicine, Oncology, Pharmacology +13

Disease-Associated Prion Protein Oligomers Inhibit the 26S Proteasome

Mark Kristiansen, Pelagia Deriziotis, Derek E. Dimcheff et al. · Molecular Cell · 2007 · 257 citations · Full text

Veterinary Medicine, Biochemistry, Molecular Biology +10