Grit S. Herter-Sprie

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

Shohei Koyama, Esra A. Akbay, Yvonne Y. Li et al. · Nature Communications · 2016 · 1.5K citations · Full text

CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation

Jiehui Deng, Eric S. Wang, Russell W. Jenkins et al. · Cancer Discovery · 2017 · 741 citations · Full text

STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment

Shohei Koyama, Esra A. Akbay, Yvonne Y. Li et al. · Cancer Research · 2016 · 605 citations · Full text

Targeting Transcriptional Addictions in Small Cell Lung Cancer with a Covalent CDK7 Inhibitor

Camilla L. Christensen, Nicholas Kwiatkowski, Brian J. Abraham et al. · Cancer Cell · 2014 · 449 citations · Full text

Medicine, Immune Checkpoint Inhibitor, Cancer Biology +6

Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression

Chunxiao Xu, Christine M. Fillmore, Shohei Koyama et al. · Cancer Cell · 2014 · 378 citations · Full text

Tumor Biology, Pten Leads, Medicine +11