Anna L. Bowman

Small Molecule Inhibitors of the MDM2-p53 Interaction Discovered by Ensemble-Based Receptor Models

Anna L. Bowman, Zaneta Nikolovska‐Coleska, Haizhen A. Zhong et al. · Journal of the American Chemical Society · 2007 · 126 citations

Small Molecule Inhibitors, Drug Target, Molecular Biology +18

QM/MM simulations predict a covalent intermediate in the hen egg white lysozyme reaction with its natural substrate

Anna L. Bowman, Ian Grant, Adrian J. Mulholland · Chemical Communications · 2008 · 71 citations

Qm/mm Simulations, Protein Folding, Macromolecular Machine +12

Novel 1′,1′-Chain Substituted Hexahydrocannabinols: 9β-Hydroxy-3-(1-hexyl-cyclobut-1-yl)-hexahydrocannabinol (AM2389) a Highly Potent Cannabinoid Receptor 1 (CB1) Agonist

Spyros P. Nikas, Shakiru O. Alapafuja, Ioannis Papanastasiou et al. · Journal of Medicinal Chemistry · 2010 · 57 citations · Full text

Sulfonyl Fluoride Inhibitors of Fatty Acid Amide Hydrolase

Shakiru O. Alapafuja, Spyros P. Nikas, Indu Bharathan et al. · Journal of Medicinal Chemistry · 2012 · 55 citations · Full text

Molecular Pharmacology, Biochemistry, Medicine +12

Protein Flexibility and Species Specificity in Structure-Based Drug Discovery:  Dihydrofolate Reductase as a Test System

Anna L. Bowman, Michael G. Lerner, Heather A. Carlson · Journal of the American Chemical Society · 2007 · 53 citations

Drug Target, Structural Bioinformatics, Biomolecular Structure Prediction +19