Jacqueline Shehadeh

Cleavage at the Caspase-6 Site Is Required for Neuronal Dysfunction and Degeneration Due to Mutant Huntingtin

Rona K. Graham, Yu Deng, Elizabeth Slow et al. · Cell · 2006 · 646 citations · Full text

Neurodegenerative Diseases, Developmental Biology, Molecular Neuroscience +10

Wild‐type huntingtin protects neurons from excitotoxicity

Blair R. Leavitt, Jeremy M. Van Raamsdonk, Jacqueline Shehadeh et al. · Journal of Neurochemistry · 2006 · 177 citations

Cultured Striatal Neurons, Neurodegenerative Diseases, Molecular Neuroscience +9

Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease

Melinda M. Zeron, Herman B. Fernandes, Claudia Krebs et al. · Molecular and Cellular Neuroscience · 2004 · 170 citations

Molecular Biology, Neuropharmacology, Degenerative Pathology +7

Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease

Jacqueline Shehadeh, Herman B. Fernandes, Melinda M. Zeron Mullins et al. · Neurobiology of Disease · 2005 · 125 citations · Full text

Striatal Neuronal Apoptosis, Cell Death, Nmda Receptor Activation +9

Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models

Rona K. Graham, Elizabeth Slow, Yu Deng et al. · Neurobiology of Disease · 2005 · 84 citations · Full text

Knockout Mouse, Mutant Huntingtin Influence, Genetic Disorder +9