Concepedia

R.L. Palte

RP

Statistics

Publications

11

Citations

283

H-Index

10

Active since

2020

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Quantitative BioSciences

United States Military Academy

Discovery Laboratories (United States)

R.L. Palte is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in drug discovery, pharmacy, and pharmacology.

ORCID

Publications per year

2020–2024

11

Publications

11

Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors

Mitchell H. Keylor, Anmol Gulati, Solomon D. Kattar et al. · Journal of Medicinal Chemistry · 2021 · 42 citations · Full text

, , +17

Allosteric Modulation of Protein Arginine Methyltransferase 5 (PRMT5)

R.L. Palte, Sebastian E. Schneider, Michael D. Altman et al. · ACS Medicinal Chemistry Letters · 2020 · 39 citations · Full text

, , +17

The Discovery of Two Novel Classes of 5,5-Bicyclic Nucleoside-Derived PRMT5 Inhibitors for the Treatment of Cancer

Ryan V. Quiroz, Michael H. Reutershan, Sebastian E. Schneider et al. · Journal of Medicinal Chemistry · 2021 · 34 citations · Full text

, , +15

Discovery and Optimization of Rationally Designed Bicyclic Inhibitors of Human Arginase to Enhance Cancer Immunotherapy

Matthew J. Mitcheltree, Derun Li, Abdelghani Achab et al. · ACS Medicinal Chemistry Letters · 2020 · 30 citations · Full text

, , +15

Structure-Based Discovery of Proline-Derived Arginase Inhibitors with Improved Oral Bioavailability for Immuno-Oncology

Min Lu, Hongjun Zhang, Derun Li et al. · ACS Medicinal Chemistry Letters · 2021 · 26 citations · Full text

, , +14

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