Simone Lieb

BI 2536, a Potent and Selective Inhibitor of Polo-like Kinase 1, Inhibits Tumor Growth In Vivo

Martin Steegmaier, Matthias Hoffmann, Anke Baum et al. · Current Biology · 2007 · 849 citations · Full text

Medicine, Oncology, Pharmacology +14

Werner syndrome helicase is a selective vulnerability of microsatellite instability-high tumor cells

Simone Lieb, Silvia Blaha-Ostermann, Elisabeth Kamper et al. · eLife · 2019 · 145 citations · Full text

Life Sciences, Genetics, Oncology +17

Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contexts

Petra van der Lelij, Simone Lieb, Julian Jude et al. · eLife · 2017 · 130 citations · Full text

Life Sciences, Genetics, Oncology +14

Triple Angiokinase Inhibitor Nintedanib Directly Inhibits Tumor Cell Growth and Induces Tumor Shrinkage via Blocking Oncogenic Receptor Tyrosine Kinases

Frank Hilberg, Ulrike Tontsch-Grunt, Anke Baum et al. · Journal of Pharmacology and Experimental Therapeutics · 2017 · 105 citations · Full text

Medicine, Oncology, Pharmacology +17

Discovery of potent and selective HER2 inhibitors with efficacy against HER2 exon 20 insertion-driven tumors, which preserve wild-type EGFR signaling

Birgit Wilding, Dirk Scharn, Dietrich Böse et al. · Nature Cancer · 2022 · 53 citations

Medicine, Medicinal Chemistry, Oncology +15