Roberto A. Chica

Iterative approach to computational enzyme design

Heidi K. Privett, Gert Kiss, Toni M. Lee et al. · Proceedings of the National Academy of Sciences · 2012 · 338 citations · Full text

Life Sciences, Biochemistry, Computational Chemistry +16

Protein Engineering, Design and Selection

Roberto A. Chica · Protein Engineering Design and Selection · 2020 · 145 citations · Full text

Engineering, Bioengineering, Biotechnology +11

Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico

Aron Broom, Rojo V. Rakotoharisoa, Michael C. Thompson et al. · Nature Communications · 2020 · 126 citations · Full text

Engineering, Biochemistry, Bioengineering +17

Generation of longer emission wavelength red fluorescent proteins using computationally designed libraries

Roberto A. Chica, Matthew M. Moore, Benjamin D. Allen et al. · Proceedings of the National Academy of Sciences · 2010 · 106 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Rational design of proteins that exchange on functional timescales

James A. Davey, Adam M. Damry, Natalie K. Goto et al. · Nature Chemical Biology · 2017 · 86 citations

Life Sciences, Biochemistry, Biophysics +14