Jonathan Finlayson

The Benzyne Fischer-Indole Reaction

Donald McAusland, Sangwon Seo, Didier Pintori et al. · Organic Letters · 2011 · 101 citations

Natural Sciences, Chemistry, Organic Chemistry +10

(1<i>R</i>,2<i>R</i>)-<i>N</i>-(1-Cyanocyclopropyl)-2-(6-methoxy-1,3,4,5-tetrahydropyrido[4,3-<i>b</i>]indole-2-carbonyl)cyclohexanecarboxamide (AZD4996): A Potent and Highly Selective Cathepsin K Inhibitor for the Treatment of Osteoarthritis

Alexander G. Dossetter, Howard A. Beeley, Jonathan Bowyer et al. · Journal of Medicinal Chemistry · 2012 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Pharmacokinetic Benefits of 3,4-Dimethoxy Substitution of a Phenyl Ring and Design of Isosteres Yielding Orally Available Cathepsin K Inhibitors

James J. Crawford, Peter W. Kenny, Jonathan Bowyer et al. · Journal of Medicinal Chemistry · 2012 · 22 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Discovery and structure–activity relationships of a novel oxazolidinone class of bacterial type II topoisomerase inhibitors

Amanda Lyons, James D. Kirkham, Kevin Blades et al. · Bioorganic & Medicinal Chemistry Letters · 2022 · 15 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases

Dearg S. Brown, John G. Cumming, Paul A. Bethel et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 11 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9