Haotian Tang

LS‐106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo

Yingqiang Liu, Mengzhen Lai, Shan Li et al. · Cancer Science · 2021 · 49 citations · Full text

Branched-chain amino acid transaminase 1 confers EGFR-TKI resistance through epigenetic glycolytic activation

Tao Zhang, Zilu Pan, Jing Gao et al. · Signal Transduction and Targeted Therapy · 2024 · 28 citations · Full text

Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors

Huanyu Shi, Haotian Tang, Yan Li et al. · European Journal of Medicinal Chemistry · 2022 · 19 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +11

Application of deep generative model for design of Pyrrolo[2,3-d] pyrimidine derivatives as new selective TANK binding kinase 1 (TBK1) inhibitors

Shukai Song, Haotian Tang, Ting Ran et al. · European Journal of Medicinal Chemistry · 2022 · 13 citations · Full text

Combinatorial Chemistry, Deep Generative Model, Biochemistry +7

Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors

Junjie Zhang, Yan Li, Haotian Tang et al. · Bioorganic Chemistry · 2023 · 13 citations