Identification of New Small-Molecule Inducers of Estrogen-related Receptor α (ERRα) Degradation

Lijie Peng, Zhensheng Zhang, Chong Lei, +7

ACS Medicinal Chemistry Letters

LS‐106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo

Yingqiang Liu, Mengzhen Lai, Shan Li, +20

Cancer Science

Curcumin prevents corticosterone‐induced neurotoxicity and abnormalities of neuroplasticity via 5‐HT receptor pathway

Ying Xu, Shan Li, Matthew M. Vernon, +11

Journal of Neurochemistry

Interannual and seasonal variations of permafrost thaw depth on the Qinghai-Tibetan Plateau: A comparative study using long short-term memory, convolutional neural networks, and random forest

Qi Liu, Jie Niu, Ping Lü, +6

The Science of The Total Environment

ClimatologyQinghai-tibetan PlateauGlacierPermafrostEngineering +9

A covalent p97/VCP ATPase inhibitor can overcome resistance to CB-5083 and NMS-873 in colorectal cancer cells

Gang Zhang, Shan Li, Feng Wang, +7

European Journal of Medicinal Chemistry

Tumor BiologyBiochemistryNatural SciencesMedicineMolecular Biology +6

Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR^T790M/C797S Mutants

Shan Li, Tao Zhang, Sujie Zhu, +11

ACS Medicinal Chemistry Letters

Nicotinamide n-Oxide Attenuates HSV-1-Induced Microglial Inflammation through Sirtuin-1/NF-κB Signaling

Xiaowei Song, Wenyan Cao, Zexu Wang, +8

International Journal of Molecular Sciences

ImmunologyImmune RegulationResident MacrophagesInnate ImmunityImmune System +17

ML-FGAT: Identification of multi-label protein subcellular localization by interpretable graph attention networks and feature-generative adversarial networks

Congjing Wang, Yifei Wang, Pengju Ding, +3

Computers in Biology and Medicine

Systems BiologyGraph Representation LearningGraph TheoryData ScienceMachine Learning +11

SNORD88B-mediated WRN nucleolar trafficking drives self-renewal in liver cancer initiating cells and hepatocarcinogenesis

Yang Gu, Zhibin Yi, Ziheng Zhou, +8

Nature Communications

1-D coupled surface flow and transport equations revisited via the physics-informed neural network approach

Jie Niu, Wei Xu, Han Qiu, +2

Journal of Hydrology