Lai Hong Wong

Accurate proteome-wide missense variant effect prediction with AlphaMissense

Jun Cheng, Guido Novati, Joshua Pan et al. · Science · 2023 · 2K citations

Life Sciences, Bioinformatics, Genetics +15

AlphaFold Protein Structure Database and 3D-Beacons: New Data and Capabilities

Jennifer Fleming, Paulyna Magaña, Sreenath Nair et al. · Journal of Molecular Biology · 2025 · 199 citations · Full text

Life Sciences, Bioinformatics, Biology +16

Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids

Visesato Mor, Antonella Rella, Amir M. Farnoud et al. · mBio · 2015 · 148 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Advancing regulatory variant effect prediction with AlphaGenome

Natasha S. Latysheva, Jun Cheng, Guido Novati et al. · Nature · 2026 · 119 citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Massively parallel characterization of CYP2C9 variant enzyme activity and abundance

Clara J. Amorosi, Melissa A. Chiasson, Matthew G. McDonald et al. · The American Journal of Human Genetics · 2021 · 117 citations · Full text

Life Sciences, Biochemistry, Genetics +13