Holly Kimko

A randomized trial of 7-day doripenem versus 10-day imipenem-cilastatin for ventilator-associated pneumonia

Marin H. Kollef, Jean Chastre, M. Clavel et al. · Critical Care · 2012 · 211 citations · Full text

Simulations of tumor growth and response to immunotherapy by coupling a spatial agent-based model with a whole-patient quantitative systems pharmacology model

Álvaro Ruiz-Martínez, Chang Gong, Hanwen Wang et al. · PLoS Computational Biology · 2022 · 56 citations · Full text

Engineering, Immunology, Spatial Agent-based Model +19

Impact of low percentage of data below the quantification limit on parameter estimates of pharmacokinetic models

Xu Steven Xu, Adrian Dunne, Holly Kimko et al. · Journal of Pharmacokinetics and Pharmacodynamics · 2011 · 37 citations

Low Percentage, Parameter Estimates, Pharmacokinetic Modeling +9

A Spatial Quantitative Systems Pharmacology Platform spQSP-IO for Simulations of Tumor–Immune Interactions and Effects of Checkpoint Inhibitor Immunotherapy

Chang Gong, Álvaro Ruiz-Martínez, Holly Kimko et al. · Cancers · 2021 · 37 citations · Full text

What Does it Take to Make Model-Informed Precision Dosing Common Practice? Report from the 1st Asian Symposium on Precision Dosing

Thomas M. Polasek, Amin Rostami‐Hodjegan, Dong‐Seok Yim et al. · The AAPS Journal · 2019 · 35 citations

Precision Dosing, Asian Symposium, Biostatistics +7