Hui‐Hwa Chang

The pharmacological chaperone 1‐deoxygalactonojirimycin increases α‐galactosidase A levels in Fabry patient cell lines

John J. Flanagan, Adriane Schilling, Hui‐Hwa Chang et al. · Journal of Inherited Metabolic Disease · 2009 · 169 citations

Mutant α-galactosidase A enzymes identified in Fabry disease patients with residual enzyme activity: biochemical characterization and restoration of normal intracellular processing by 1-deoxygalactonojirimycin

Hui‐Hwa Chang, Kunito Kawasaki, Kayo Yasuda et al. · Biochemical Journal · 2007 · 144 citations · Full text

Hydrophilic iminosugar active‐site‐specific chaperones increase residual glucocerebrosidase activity in fibroblasts from Gaucher patients

Hui‐Hwa Chang, Naoki Asano, Yoshitaka Ichikawa et al. · FEBS Journal · 2006 · 126 citations · Full text

Rational Design and Synthesis of Highly Potent β‐Glucocerebrosidase Inhibitors

Xiaoxiang Zhu, Kamlesh A. Sheth, Shihong Li et al. · Angewandte Chemie International Edition · 2005 · 100 citations

Hydrophobic Binding Sites, Glycobiology, Peptide Science +19

Migalastat HCl Reduces Globotriaosylsphingosine (Lyso-Gb3) in Fabry Transgenic Mice and in the Plasma of Fabry Patients

Brandy Young-Gqamana, Nastry Brignol, Hui‐Hwa Chang et al. · PLoS ONE · 2013 · 47 citations · Full text

Human Growth, Fabry Transgenic Mice, Migalastat Hcl Reduces +17