Hui‐Hwa Chang - Concepedia

Author

Hui‐Hwa Chang

Icahn School of Medicine at Mount Sinai

Also Known As

H Chang, H. H. Chang, H.-H. Chang, Hui-Hwa Chang, Hui‐Hwa Chang

Publications

683

Citations

H-Index

Concepts

All Affiliations

Icahn School of Medicine at Mount Sinai Amicus Therapeutics (United States)

About

Hui‐Hwa Chang is an author at Icahn School of Medicine at Mount Sinai specializing in medicine, pharmacology, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	205
2	Biochemistry	3	3	158
3	Natural Sciences	2	2	138
4	Engineering	1	1	20
5	Biomolecular Engineering	1	1	20

Hui‐Hwa Chang

Publications

682

Citations

H-Index

Page 1

	Year	Citations
The pharmacological chaperone 1‐deoxygalactonojirimycin increases α‐galactosidase A levels in Fabry patient cell lines John J. Flanagan, Adriane Schilling, Hui‐Hwa Chang, Journal of Inherited Metabolic Disease	2009	169
Mutant α-galactosidase A enzymes identified in Fabry disease patients with residual enzyme activity: biochemical characterization and restoration of normal intracellular processing by 1-deoxygalactonojirimycin Hui‐Hwa Chang, Kunito Kawasaki, Kayo Yasuda, Biochemical Journal	2007	144
Hydrophilic iminosugar active‐site‐specific chaperones increase residual glucocerebrosidase activity in fibroblasts from Gaucher patients Hui‐Hwa Chang, Naoki Asano, Yoshitaka Ichikawa, FEBS Journal	2006	126
Rational Design and Synthesis of Highly Potent β‐Glucocerebrosidase Inhibitors Xiaoxiang Zhu, Kamlesh A. Sheth, Shihong Li, Angewandte Chemie International Edition Hydrophobic Binding SitesGlycobiologyPeptide SciencePharmacotherapySubstrate Reduction Therapy	2005	100
Migalastat HCl Reduces Globotriaosylsphingosine (Lyso-Gb3) in Fabry Transgenic Mice and in the Plasma of Fabry Patients Brandy Young-Gqamana, Nastry Brignol, Hui‐Hwa Chang, PLoS ONE Human GrowthFabry Transgenic MiceMigalastat Hcl ReducesImmunologyGlycobiology	2013	47
Rational Design and Synthesis of Highly Potent β‐Glucocerebrosidase Inhibitors Xiaoxiang Zhu, Kamlesh A. Sheth, Shihong Li, Angewandte Chemie Gaucher-krankheit Wurden SynthetisiertPharmacotherapyPharmaceutical ChemistryPre-clinical PharmacologyMolecular Pharmacology	2005	38
Preclinical Efficacy and Safety of 1-Deoxygalactonojirimycin in Mice for Fabry Disease Hui‐Hwa Chang, Hidekatsu Yoshioka, Tatsuo Shimada, Journal of Pharmacology and Experimental Therapeutics	2008	38
Efficient and rapid purification of recombinant human α-galactosidase A by affinity column chromatography Kayo Yasuda, Hui‐Hwa Chang, Huili Wu, Protein Expression and Purification EngineeringGlycosylationBiochemistryRapid PurificationBioanalysis	2004	20

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