W. Edward Highsmith

Clinical and biologic activity of the farnesyltransferase inhibitor R115777 in adults with refractory and relapsed acute leukemias: a phase 1 clinical-laboratory correlative trial

Judith E. Karp, Jeffrey E. Lancet, Scott H. Kaufmann et al. · Blood · 2001 · 445 citations · Full text

A mutation in CFTR produces different phenotypes depending on chromosomal background

Sandra Kiesewetter, Milan Maçek, Claire Davis et al. · Nature Genetics · 1993 · 440 citations

Genetic Disorder, Genetics, Chromosomal Background +7

A Novel Mutation in the Cystic Fibrosis Gene in Patients with Pulmonary Disease but Normal Sweat Chloride Concentrations

W. Edward Highsmith, Lauranell H. Burch, Zhaoqing Zhou et al. · New England Journal of Medicine · 1994 · 437 citations · Full text

A Common Trinucleotide Repeat Expansion within the Transcription Factor 4 (TCF4, E2-2) Gene Predicts Fuchs Corneal Dystrophy

Eric D. Wieben, Ross A. Aleff, Nirubol Tosakulwong et al. · PLoS ONE · 2012 · 276 citations · Full text

Genetics, Immunology, Genetic Epidemiology +19

Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma

Benjamin R. Kipp, Jesse S. Voss, Sarah E. Kerr et al. · Human Pathology · 2012 · 238 citations

Tumor Biology, Isocitrate Dehydrogenase 1, Biliary Cancer +6