Dominic Surry

Validation and application of Caco-2 assays for the<b><i>in vitro</i></b>evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions

Robert Elsby, Dominic Surry, Veronica Smith et al. · Xenobiotica · 2008 · 141 citations

Pharmaceutical Science, Cellular Pharmacology, Development Candidate Drugs +24

Antagonists of the Human A_2A Adenosine Receptor. 4. Design, Synthesis, and Preclinical Evaluation of 7-Aryltriazolo[4,5-<i>d</i>]pyrimidines

Roger J. Gillespie, Samantha J. Bamford, Ruth Botting et al. · Journal of Medicinal Chemistry · 2008 · 103 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Striatal Dopamine +14

Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure

Robert Elsby, Paul Martin, Dominic Surry et al. · Drug Metabolism and Disposition · 2015 · 95 citations

Gene expression profiling of drug metabolism and toxicology markers using a low-density DNA microarray

Françoise de Longueville, Dominic Surry, Georgina Meneses‐Lorente et al. · Biochemical Pharmacology · 2002 · 70 citations

Functional Genomics, Predictive Toxicology, Medicine +11

Comparison of the effects of some CYP3A and other enzyme inducers on replicative DNA synthesis and cytochrome P450 isoforms in rat liver

Brian G. Lake, A. B. Renwick, Morag E. Cunninghame et al. · Toxicology · 1998 · 60 citations

Biochemistry, Medicine, Liver Physiology +11