Concepedia
4
Publications
104
Citations
H-Index
2022
Active since
Affiliations
MRC Mitochondrial Biology Unit(Current)
University of Cambridge
Madeleine J. Twyning is an author at MRC Mitochondrial Biology Unit.
Publications per year
2022–2024
Decreasing pdzd8-mediated mito–ER contacts improves organismal fitness and mitigates Aβ <sub>42</sub> toxicity
Victoria L. Hewitt, Leonor Miller‐Fleming, Madeleine J. Twyning et al. · Life Science Alliance · 2022 · 39 citations · Full text
Mitochondrial CISD1/Cisd accumulation blocks mitophagy and genetic or pharmacological inhibition rescues neurodegenerative phenotypes in Pink1/parkin models
Aitor Martinez, Álvaro Sánchez-Martínez, Jake T. Pickering et al. · Molecular Neurodegeneration · 2024 · 33 citations · Full text
Partial loss of MCU mitigates pathology in vivo across a diverse range of neurodegenerative disease models
Madeleine J. Twyning, Roberta Tufi, Thomas P. Gleeson et al. · Cell Reports · 2024 · 19 citations · Full text
Activation of the Keap1/Nrf2 pathway suppresses mitochondrial dysfunction, oxidative stress, and motor phenotypes in <i>C9orf72</i> ALS/FTD models
Wing Hei Au, Leonor Miller‐Fleming, Álvaro Sánchez-Martínez et al. · Life Science Alliance · 2024 · 13 citations · Full text
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