UV-B Radiation Induces Epithelial Tumors in Mice Lacking DNA Polymerase η and Mesenchymal Tumors in Mice Deficient for DNA Polymerase ι

Tsuyoshi Ohkumo, Yuji Kondo, Masayuki Yokoi, +9

Molecular and Cellular Biology

EngineeringRadiation EffectPathologyDermatologyRadiation Biology +22

USP7 Is a Suppressor of PCNA Ubiquitination and Oxidative-Stress-Induced Mutagenesis in Human Cells

Shu-ichiro Kashiwaba, Rie Kanao, Yuji Masuda, +3

Cell Reports

Different types of interaction between PCNA and PIP boxes contribute to distinct cellular functions of Y-family DNA polymerases

Yuji Masuda, Rie Kanao, Kentaro Kaji, +3

Nucleic Acids Research

Molecular RegulationGeneticsDna AnalysisMolecular BiologyTranslesion Dna Synthesis +18

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication

Toshihiro Shibutani, Shinsuke Ito, Mariko Toda, +11

Scientific Reports

Regulation of HLTF-mediated PCNA polyubiquitination by RFC and PCNA monoubiquitination levels determines choice of damage tolerance pathway

Yuji Masuda, Satoshi Mitsuyuki, Rie Kanao, +3

Nucleic Acids Research

Molecular RegulationGeneticsGenomic MechanismMolecular BiologyDamage Tolerance Pathway +20

UV-induced mutations in epidermal cells of mice defective in DNA polymerase η and/or ι

Rie Kanao, Masayuki Yokoi, Tsuyoshi Ohkumo, +7

DNA repair

Genome InstabilityNatural SciencesGeneticsCutaneous BiologyDna Replication +8

Preferential digestion of PCNA-ubiquitin and p53-ubiquitin linkages by USP7 to remove polyubiquitin chains from substrates

Yuji Masuda, Rie Kanao, Hidehiko Kawai, +2

Journal of Biological Chemistry

Relevance of Simultaneous Mono-Ubiquitinations of Multiple Units of PCNA Homo-Trimers in DNA Damage Tolerance

Rie Kanao, Yuji Masuda, Saori Deguchi, +3

PLoS ONE

Dna Damage ToleranceDna DamageGeneticsDna AnalysisMolecular Biology +14

Novel mechanisms for the removal of strong replication-blocking HMCES- and thiazolidine-DNA adducts in humans

Yohei Sugimoto, Yuji Masuda, Shigenori Iwai, +3

Nucleic Acids Research

Thiazolidine-dna AdductsGeneticsMolecular BiologyNucleic Acid ChemistryProtein Degradation +16

A novel interaction between human DNA polymerase η and MutLα

Rie Kanao, Fumio Hanaoka, Chikahide Masutani

Biochemical and Biophysical Research Communications

Polymerase Chain ReactionTranscriptional RegulationNucleic Acid ChemistryNatural SciencesGenetics +9