N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer

Étienne Dardenne, Himisha Beltran, Matteo Benelli, +18

Cancer Cell

Transcriptional RegulationMedicineCell BiologyProstatic DiseaseOncology +3

A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers

Himisha Beltran, Clara Oromendia, Daniel C. Danila, +23

Clinical Cancer Research

RNA Helicases DDX5 and DDX17 Dynamically Orchestrate Transcription, miRNA, and Splicing Programs in Cell Differentiation

Étienne Dardenne, Micaela Polay Espinoza, Laurent Fattet, +15

Cell Reports

Delta-like protein 3 expression and therapeutic targeting in neuroendocrine prostate cancer

Loredana Puca, Katie Gavyert, Verena Sailer, +21

Science Translational Medicine

N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer

Adeline Berger, Nicholas J. Brady, Rohan Bareja, +17

Journal of Clinical Investigation

Cotranscriptional exon skipping in the genotoxic stress response

Martin Dutertre, Gabriel Sanchez, Marie‐Cécile De Cian, +7

Nature Structural & Molecular Biology

StressGeneticsCotranscriptional ExonGenetic Factor

Splicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasiveness

Étienne Dardenne, Sandra Pierredon, Keltouma Driouch, +11

Nature Structural & Molecular Biology

ChromatinChromatin RemodelingMedicineRna SplicingEpigenetic Regulator +9

Estrogen Regulation and Physiopathologic Significance of Alternative Promoters in Breast Cancer

Martin Dutertre, Lise Gratadou, Étienne Dardenne, +6

Cancer Research

Transcriptional RegulationBreast OncologyFunctional GenomicsHormonal ReceptorGenetics +12

Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor

Sophie Germann, Lise Gratadou, Eleonora Zonta, +7

Oncogene

Transcriptional RegulationDdx5/ddx17 RnaDual RoleGeneticsNatural Sciences +8

The Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathways

Samaan Samaan, Léon-Charles Tranchevent, Étienne Dardenne, +6

Nucleic Acids Research

GeneticsMolecular BiologyAndrogen ReceptorsSplicing VariantMammary Gland Development +20