Simon N. Owen

Statistics

Publications

Citations

480

H-Index

Active since

1993

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

MSD (UK) Limited (United Kingdom)

Simon N. Owen is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in pharmacology, molecular pharmacology, and medicinal chemistry.

Publications per year

1993–2002

Publications

Pharmacological blockade or genetic deletion of substance P (NK1) receptors attenuates neonatal vocalisation in guinea-pigs and mice

N.M.J. Rupniak, E.C Carlson, Timothy Harrison et al. · Neuropharmacology · 2000 · 171 citations

Medicine, Neurobiology, Pharmacology +8

In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists

N.M.J. Rupniak, F.D. Tattersall, Angela Williams et al. · European Journal of Pharmacology · 1997 · 117 citations

Medicine, Pharmacology, Pharmacotherapy +4

<i>N</i>-Heteroaryl-2-phenyl-3-(benzyloxy)piperidines: A Novel Class of Potent Orally Active Human NK<sub>1</sub> Antagonists

T. Ladduwahetty, R. Baker, Margaret A. Cascieri et al. · Journal of Medicinal Chemistry · 1996 · 66 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Identification of a Series of 3-(Benzyloxy)-1-azabicyclo[2.2.2]octane Human NK1 Antagonists

Christopher J. Swain, Eileen M. Sewart, Margaret A. Cascieri et al. · Journal of Medicinal Chemistry · 1995 · 43 citations · Full text

Natural Sciences, Medicinal Chemistry, Pharmacology +9

Quinuclidine-based NK-1 antagonists I: 3-benzyloxy-1-azabicyclo[2.2.2]octanes

Eileen M. Seward, Christopher J. Swain, Kevin J. Merchant et al. · Bioorganic & Medicinal Chemistry Letters · 1993 · 28 citations

Medicine, Medicinal Chemistry, Pharmacology +7

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